3 papers
stat.OT2026
Statistical Methodology Groups in the Pharmaceutical Industry
Jenny Devenport, Tobias Mielke, Mouna Akacha +10
Research and Development is the largest budget position in the pharmaceutical industry, with clinical trials being a critical, yet costly and time-consuming component to inform dec…
stat.ME2026
Revealing the Truth: Calculating True Values in Causal Inference Simulation Studies via Gaussian Quadrature
Alex Ocampo, Enrico Giudice, Zachary R. McCaw +1
Simulation studies are used to understand the properties of statistical methods. A key luxury in many simulation studies is knowledge of the true value (i.e. the estimand) being ta…
stat.ME2024
Simplifying Causal Mediation Analysis for Time-to-Event Outcomes using Pseudo-Values
Alex Ocampo, Enrico Giudice, Dieter A. Häring +3
Mediation analysis for survival outcomes is challenging. Most existing methods quantify the treatment effect using the hazard ratio (HR) and attempt to decompose the HR into the di…