3 papers
q-bio.CB2026
The spontaneous emergence of leaders and followers in a mathematical model of cranial neural crest cell migration
Samuel W. S. Johnson, Ruth E. Baker, Philip K. Maini
Many agent-based mathematical models of cranial neural crest cell (CNCC) migration impose a binary phenotypic partition of cells into either leaders or followers. In such models, t…
q-bio.CB2025
An energy-based mathematical model of actin-driven protrusions in eukaryotic chemotaxis
Samuel W. S. Johnson, Maddy Parsons, Ruth E. Baker +1
In eukaryotic cell chemotaxis, cells extend and retract transient actin-driven protrusions at their membrane that facilitate both the detection of external chemical gradients and d…
q-bio.PE2025
Modelling the impact of phenotypic heterogeneity on cell migration: a continuum framework derived from individual-based principles
Rebecca M. Crossley, Philip K. Maini, Ruth E. Baker
Collective cell migration plays a crucial role in numerous biological processes, including tumour growth, wound healing, and the immune response. Often, the migrating population co…