activity
20242026
most citedODesign: A World Model for Biomolecular Interaction Design

3 citations · 6 across the 11 of their papers we have counts for

collaborators

13 papers

cs.AI2026

Learning from Unverified Peers via Shared Residual Distillation

Feiyang Chen, Runze Ma, Zichen Wang +4

A language model can generate several solutions to the same problem, some leading to correct answers and others to incorrect ones. Many post-training methods turn these trajectorie…

cs.LG2026

TRACE: Tractable Routing Autoencoder for Clinical ECG

Shunbo Jia, Runze Ma, Haonan Lyu +3

Deep learning has advanced automated electrocardiogram (ECG) diagnosis, but the field's most accurate models, foundation models pretrained on millions of recordings, are not decisi…

q-bio.BM2026

Antigen-specific Antibody Multi-modal Foundation Model for Functional Antibody Design

Xiaoliang Shi, Zichen Wang, Runze Ma +2

Antibodies are essential proteins that play a central role in immune recognition by binding specific antigen molecules. Although recent protein language models have enabled progres…

cs.LG2026

REALM: Retrospective Encoder Alignment for LFP Modeling

Peicheng Wu, Zhenyu Bu, Runze Ma +1

Spike activity has been the dominant neural signal for behavior decoding because its high spatiotemporal resolution supports accurate decoding. However, as intracortical brain-comp…

cs.CV2026

LiteMedCoT-VL: Parameter-Efficient Adaptation for Medical Visual Question Answering

Runze Ma, Shunbo Jia, Haonan Lyu +2

The reasoning gap between large and compact vision-language models (VLMs) limits the deployment of medical AI on portable clinical devices. Compact VLMs of 2-4B parameters can run…

cs.LG2026

BEAT-Net: Injecting Biomimetic Spatio-Temporal Priors for Interpretable ECG Diagnosis

Runze Ma, Haonan Lyu, Caizhi Liao +5

Automated electrocardiogram diagnosis using deep learning remains limited by signal-agnostic representations that treat multi-lead recordings as undifferentiated time-series or ima…

q-bio.CB2025★ 2 cited

VCWorld: A Biological World Model for Virtual Cell Simulation

Zhijian Wei, Runze Ma, Zichen Wang +3

Virtual cell modeling aims to predict cellular responses to perturbations. Existing virtual cell models rely heavily on large-scale single-cell datasets, learning explicit mappings…

q-bio.GN2025★ 1 cited

NABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction

Zhongmin Li, Runze Ma, Jiahao Tan +2

Nucleotide sequence variation can induce significant shifts in functional fitness. Recent nucleotide foundation models promise to predict such fitness effects directly from sequenc…

q-bio.BM2025★ 3 cited

ODesign: A World Model for Biomolecular Interaction Design

Odin Zhang, Xujun Zhang, Haitao Lin +34

Biomolecular interactions underpin almost all biological processes, and their rational design is central to programming new biological functions. Generative AI models have emerged…

cs.LG2025

Fitness aligned structural modeling enables scalable virtual screening with AuroBind

Zhongyue Zhang, Jiahua Rao, Jie Zhong +22

Most human proteins remain undrugged, over 96% of human proteins remain unexploited by approved therapeutics. While structure-based virtual screening promises to expand the druggab…

q-bio.BM2025

An Energy-Adaptive Elastic Equivariant Transformer Framework for Protein Structure Representation

Zhongyue Zhang, Runze Ma, Yanjie Huang +1

Structure-informed protein representation learning is essential for effective protein function annotation and \textit{de novo} design. However, the presence of inherent noise in bo…

q-bio.BM2025

RiboFlow: Conditional De Novo RNA Co-Design via Synergistic Flow Matching

Runze Ma, Zhongyue Zhang, Zichen Wang +4

Ribonucleic acid (RNA) binds to molecules to achieve specific biological functions. While generative models are advancing biomolecule design, existing methods for designing RNA tha…

cs.CV2024

Stacking-Enhanced Bagging Ensemble Learning for Breast Cancer Classification with CNN

Peihceng Wu, Runze Ma, Teoh Teik Toe

This paper proposes a CNN classification network based on Bagging and stacking ensemble learning methods for breast cancer classification. The model was trained and tested on the p…