10 papers
BRIDGE: Selective Boundary Repair with Dependency Graph Evidence in Multi-Agent Systems
Encheng Su, Pengze Li, Ziheng Hua +11
Multi-agent collaboration has emerged as a critical paradigm for tackling complex, long-horizon tasks; however, while coordination protocols continue to advance, systemic failures…
PROTEAN: Beyond De Novo Generation - Can LLM Agents Perform Text-Guided Protein Structure Editing?
Encheng Su, Xinping Liu, Yizhou Wang +11
Generative AI has achieved remarkable success in de novo protein design, yet protein engineering typically begins with existing, characterized proteins. The primary demand is targe…
DAPD: Dual-Anchored Policy Distillation
Jianyu Wu, Yizhou Wang, Encheng Su +2
On-policy (self) distillation (OPSD) is increasingly adopted for language-model post-training. It strengthens the teacher with privileged information but can induce a privilege ill…
Accurate, Interdisciplinary and Transparent Structure-property Understanding with Deep Native Structural Reasoning
Chen Tang, Yizhou Wang, Jianyu Wu +26
Structure-property relationships are foundational to biology, chemistry and materials science, where function, reactivity and physical response emerge from spatial, chemical and pe…
S3Mem: Structured Spatiotemporal Scene-Event Memory for Long-Horizon Interactive Question Answering
Encheng Su, Jianyu Wu, Jinouwen Zhang +9
Long-horizon memory question answering often requires sparse evidence from heterogeneous histories, including events, object states, visual observations, temporal relations, and ca…
LECTOR: Joint Optimization of Scientific Reasoning Graphs and Introduction Generation
Jiabei Xiao, Yizhou Wang, Chen Tang +3
AI Scientists have shown promising progress across multiple stages of the research pipeline, among which automatic scientific paper writing remains a formidable challenge. The Intr…
SciIF: Benchmarking Scientific Instruction Following Towards Rigorous Scientific Intelligence
Encheng Su, Jianyu Wu, Chen Tang +9
As large language models (LLMs) transition from general knowledge retrieval to complex scientific discovery, their evaluation standards must also incorporate the rigorous norms of…
Probing Scientific General Intelligence of LLMs with Scientist-Aligned Workflows
Wanghan Xu, Yuhao Zhou, Yifan Zhou +104
Despite advances in scientific AI, a coherent framework for Scientific General Intelligence (SGI)-the ability to autonomously conceive, investigate, and reason across scientific do…
SciReasoner: Laying the Scientific Reasoning Ground Across Disciplines
Yizhou Wang, Chen Tang, Han Deng +29
We present a scientific reasoning foundation model that aligns natural language with heterogeneous scientific representations. The model is pretrained on a 206B-token corpus spanni…
UniSTD: Towards Unified Spatio-Temporal Learning across Diverse Disciplines
Chen Tang, Xinzhu Ma, Encheng Su +6
Traditional spatiotemporal models generally rely on task-specific architectures, which limit their generalizability and scalability across diverse tasks due to domain-specific desi…