Showing 2024 · stat.MEShow all
3 papers · 2 filters
stat.ME2024
From Estimands to Robust Inference of Treatment Effects in Master Protocol Trials
Yuhan Qian, Yifan Yi, Jun Shao +5
Master protocol trials use a single overarching protocol to evaluate multiple interventions, diseases, or disease subtypes, where individuals are often randomized to different subs…
stat.ME2024
Improve the Precision of Area Under the Curve Estimation for Recurrent Events Through Covariate Adjustment
Jiren Sun, Tuo Wang, Yanyao Yi +3
The area under the curve (AUC) of the mean cumulative function (MCF) has recently been introduced as a novel estimand for evaluating treatment effects in recurrent event settings,…
stat.ME2024
Clarifying the Role of the Mantel-Haenszel Risk Difference Estimator in Randomized Clinical Trials
Xiaoyu Qiu, Yuhan Qian, Jaehwan Yi +4
The Mantel-Haenszel (MH) risk difference estimator, commonly used in randomized clinical trials for binary outcomes, calculates a weighted average of stratum-specific risk differen…