4 papers
MTCurv: Deep learning for direct microtubule curvature mapping in noisy fluorescence microscopy images
Achraf Ait Laydi, Sidi Mohamed Sid'El Moctar, Yousef El Mourabit +1
Accurate quantification of the geometry of curvilinear biological structures is essential for understanding cellular mechanics and disease-related morphological alterations. Microt…
MTFlow: Time-Conditioned Flow Matching for Microtubule Segmentation in Noisy Microscopy Images
Sidi Mohamed Sid El Moctar, Achraf Ait Laydi, Yousef El Mourabit +1
Microtubules are cytoskeletal filaments that play essential roles in many cellular processes and are key therapeutic targets in several diseases. Accurate segmentation of microtubu…
Kinesin-12 KLP-18 contributes to the kinetochore-microtubule poleward flux during the metaphase of C. elegans one-cell embryo
Nina Soler, Mathis Da Silva, Christophe Tascon +6
The mitotic spindle partitions chromosomes during cell division by connecting the poles to kinetochores through microtubules (MTs). Their plus-ends, facing the chromosomes, exhibit…
A novel attention mechanism for noise-adaptive and robust segmentation of microtubules in microscopy images
Achraf Ait Laydi, Louis Cueff, Mewen Crespo +2
Segmenting cytoskeletal filaments in microscopy images is essential for studying their roles in cellular processes. However, this task is highly challenging due to the fine, densel…