activity
20232026
most citedA transportable hyperspectral imaging setup based on fast, high-density spectral scanning for in situ quantitative biochemical mapping of fresh tissue biopsies

9 citations · 9 across the 10 of their papers we have counts for

collaborators

13 papers

physics.med-ph2026

A Multimodal Hyperspectral and Laser Speckle Imaging Platform for Simultaneous Monitoring of Spinal Cord Oxygenation, Perfusion and Metabolism

Junda Wang, Luca Giannoni, Ayse Gertrude Yenicelik +3

Hyperspectral imaging (HSI) enables spatial mapping of haemoglobin oxygenation and cytochrome-c-oxidase (CCO) redox changes in exposed neural tissue. In this study, we present a te…

physics.med-ph2026

The FetalSenseM V2: a wearable and wireless, multi-wavelength NIRS device for continuous monitoring of placental oxygenation and metabolism

Luca Giannoni, Frederic Lange, Musa Talati +9

We present here the FetalSenseM V2 (FSM V2), a wireless and wearable, multi-wavelength, NIRS device, based on LED illumination at six NIR wavelengths (782, 800, 818, 830, 848 and 8…

physics.optics2026

A unified perspective on wavelength selection for molecular composition inference from diffuse spectroscopy

Kevin Scibilia, Marcel Rosier, Luca Giannoni +6

Optical monitoring of living tissue targeting quantification of molecular composition is an active area of research. In the case of broadband spectroscopy, one can attempt to extra…

physics.med-ph2026

OptoCENTAL: a standardised, bench-testing platform based on phantoms for validating optical systems aimed at clinical monitoring of the placenta

Luca Giannoni, Uzair Hakim, Fréderic Lange +6

Optical imaging and spectroscopy solutions, such as near-infrared spectroscopy (NIRS) and diffuse optical tomography (DOT), have the potential to provide compact, bedside monitorin…

physics.med-ph2026

Hyperspectral imaging solutions for brain tissue metabolic and haemodynamic monitoring: an updated perspective

Luca Giannoni, Frédéric Lange, Ilias Tachtsidis

Since the publication of our review article Hyperspectral imaging solutions for brain tissue metabolic and hemodynamic monitoring: past, current and future developments in 2018, th…

physics.med-ph2026

Multimodal Imaging System Combining Hyperspectral and Laser Speckle Imaging for In Vivo Hemodynamic and Metabolic Monitoring

Junda Wang, Luca Giannoni, Ayse Gertrude Yenicelik +4

We present the development and validation of a novel multimodal optical imaging platform that integrates hyperspectral imaging (HSI) and laser speckle contrast imaging (LSCI) to en…

physics.med-ph2025

2bNIRS: a portable, multi-distance, broadband oximeter and cytochrome-c-oxidase monitoring system for in vivo applications

Luca Giannoni, Archie Barraclough, Chiara Carnati +2

Conventional near-infrared spectroscopy (NIRS) instruments typically employ 2-3 wavelengths for monitoring tissue haemodynamics. However, the use of broadband illumination (hundred…

physics.med-ph2025

Optimization of continuous-wave NIRS devices for placental monitoring. A simulation study

Charly Caredda, Frédéric Lange, Uzair Hakim +8

Near infrared spectroscopy (NIRS) is an optical technique that is widely used to monitor tissue oxygenation. These devices take advantage of the near infrared light to monitor deep…

physics.med-ph2025

Redefining spectral unmixing for in-vivo brain tissue analysis from hyperspectral imaging

Martin Hartenberger, Huzeyfe Ayaz, Fatih Ozlugedik +12

In this paper, we propose a methodology for extracting molecular tumor biomarkers from hyperspectral imaging (HSI), an emerging technology for intraoperative tissue assessment. To…

physics.med-ph2024

A Novel Portable and Wearable Broadband Near-Infrared Spectroscopy Device for In-Vivo Oxygenation and Metabolism Measurements

Musa Talati, Frederic Lange, Dimitrios Airantzis +11

Broadband NIRS (bNIRS) is an extension of fNIRS that provides the same assessment of oxygenation biomarkers along with a valuable marker for oxygen metabolism at a cellular level,…

physics.med-ph2024★ 9 cited

A transportable hyperspectral imaging setup based on fast, high-density spectral scanning for in situ quantitative biochemical mapping of fresh tissue biopsies

Luca Giannoni, Marta Marradi, Kevin Scibilia +11

Histopathological examination of surgical biopsies, such as in glioma and glioblastoma resection, is hindered in current clinical practice by the long times required for the labora…

physics.bio-ph2023

Learnable real-time inference of molecular composition from diffuse spectroscopy of brain tissue

Ivan Ezhov, Kevin Scibilia, Luca Giannoni +8

Diffuse optical modalities such as broadband near-infrared spectroscopy (bNIRS) and hyperspectral imaging (HSI) represent a promising alternative for low-cost, non-invasive, and fa…

q-bio.QM2023

Identifying chromophore fingerprints of brain tumor tissue on hyperspectral imaging using principal component analysis

Ivan Ezhov, Luca Giannoni, Suprosanna Shit +5

Hyperspectral imaging (HSI) is an optical technique that processes the electromagnetic spectrum at a multitude of monochromatic, adjacent frequency bands. The wide-bandwidth spectr…