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stat.ME2026
Covariate Adjustment for Wilcoxon Two Sample Statistic and Test
Zhilan Lou, Jun Shao, Ting Ye +3
We apply covariate adjustment to the Wincoxon two sample statistic and Wincoxon-Mann-Whitney test in comparing two treatments. The covariate adjustment through calibration not only…
stat.ME2026
Competing Risk Analysis in Cardiovascular Outcome Trials: A Simulation Comparison of Cox and Fine-Gray Models
Tuo Wang, Yu Du
Cardiovascular outcome trials commonly face competing risks when non-CV death prevents observation of major adverse cardiovascular events (MACE). While Cox proportional hazards mod…
stat.ME2026
Capturing Cumulative Disease Burden in Chronic Kidney Disease Outcome Trials: Area Under the Curve and Restricted Mean Time in Favor of Treatment Beyond Conventional Time-to-First Analysis
Jiren Sun, Tuo Wang, Yu Du
Chronic kidney disease (CKD) affects millions worldwide and progresses irreversibly through stages culminating in end-stage renal disease (ESRD) and death. Outcome trials in CKD tr…