4 papers
HiST: A Hierarchical Sparse Transformer for Cross-Modal Spatial Transcriptomics Modeling
Weiyi Wu, Xinwen Xu, Xingjian Diao +4
Spatial transcriptomics (ST) links gene expression with tissue morphology but remains expensive and low-throughput, motivating surrogates that infer expression from routine histolo…
Learning Spatial-Preserving Hierarchical Representations for Digital Pathology
Weiyi Wu, Xingjian Diao, Chunhui Zhang +4
Whole slide images (WSIs) pose fundamental computational challenges due to their gigapixel resolution and the sparse distribution of informative regions. Existing approaches often…
Exploiting Label-Independent Regularization from Spatial Dependencies for Whole Slide Image Analysis
Weiyi Wu, Xinwen Xu, Chongyang Gao +3
Whole slide images, with their gigapixel-scale panoramas of tissue samples, are pivotal for precise disease diagnosis. However, their analysis is hindered by immense data size and…
Assessing and Mitigating Medical Knowledge Drift and Conflicts in Large Language Models
Weiyi Wu, Xinwen Xu, Chongyang Gao +4
Large Language Models (LLMs) have great potential in the field of health care, yet they face great challenges in adapting to rapidly evolving medical knowledge. This can lead to ou…