1 citations · 1 across the 1 of their papers we have counts for
3 papers
Disentangling multispecific antibody function with graph neural networks
Joshua Southern, Changpeng Lu, Santrupti Nerli +4
Multispecific antibodies offer transformative therapeutic potential by engaging multiple epitopes simultaneously, yet their efficacy is an emergent property governed by complex mol…
Tokenizing Loops of Antibodies
Ada Fang, Robert G. Alberstein, Simon Kelow +1
The complementarity-determining regions of antibodies are loop structures that are key to their interactions with antigens, and of high importance to the design of novel biologics.…
Conformation-Aware Structure Prediction of Antigen-Recognizing Immune Proteins
Frédéric A. Dreyer, Jan Ludwiczak, Karolis Martinkus +8
We introduce Ibex, a pan-immunoglobulin structure prediction model that achieves state-of-the-art accuracy in modeling the variable domains of antibodies, nanobodies, and T-cell re…