3 citations · 4 across the 2 of their papers we have counts for
3 papers
Disentangling multispecific antibody function with graph neural networks
Joshua Southern, Changpeng Lu, Santrupti Nerli +4
Multispecific antibodies offer transformative therapeutic potential by engaging multiple epitopes simultaneously, yet their efficacy is an emergent property governed by complex mol…
Concept Bottleneck Language Models For protein design
Aya Abdelsalam Ismail, Tuomas Oikarinen, Amy Wang +8
We introduce Concept Bottleneck Protein Language Models (CB-pLM), a generative masked language model with a layer where each neuron corresponds to an interpretable concept. Our arc…
Generalists vs. Specialists: Evaluating LLMs on Highly-Constrained Biophysical Sequence Optimization Tasks
Angelica Chen, Samuel D. Stanton, Frances Ding +6
Although large language models (LLMs) have shown promise in biomolecule optimization problems, they incur heavy computational costs and struggle to satisfy precise constraints. On…