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q-bio.BM2026
MuCO: Generative Peptide Cyclization Empowered by Multi-stage Conformation Optimization
Yitian Wang, Fanmeng Wang, Angxiao Yue +3
Modeling peptide cyclization is critical for the virtual screening of candidate peptides with desirable physical and pharmaceutical properties. This task is challenging because a c…
cs.CL2026
ReGuLaR: Variational Latent Reasoning Guided by Rendered Chain-of-Thought
Fanmeng Wang, Haotian Liu, Guojiang Zhao +2
While Chain-of-Thought (CoT) significantly enhances the performance of Large Language Models (LLMs), explicit reasoning chains introduce substantial computational redundancy. Recen…