5 papers
iSight: Towards expert-AI co-assessment for improved immunohistochemistry staining interpretation
Jacob S. Leiby, Jialu Yao, Pan Lu +17
Immunohistochemistry (IHC) provides information on protein expression in tissue sections and is commonly used to support pathology diagnosis and disease triage. While AI models for…
PaperSearchQA: Learning to Search and Reason over Scientific Papers with RLVR
James Burgess, Jan N. Hansen, Duo Peng +5
Search agents are language models (LMs) that reason and search knowledge bases (or the web) to answer questions; recent methods supervise only the final answer accuracy using reinf…
A path towards AI-scale, interoperable biological data
Brian Aevermann, Andrea Califano, Chi-Li Chiu +27
Biology is at the precipice of a new era where AI accelerates and amplifies the ability to study how cells operate, organize, and work as systems, revealing why disease happens and…
MicroVQA: A Multimodal Reasoning Benchmark for Microscopy-Based Scientific Research
James Burgess, Jeffrey J Nirschl, Laura Bravo-Sánchez +20
Scientific research demands sophisticated reasoning over multimodal data, a challenge especially prevalent in biology. Despite recent advances in multimodal large language models (…
CellFlux: Simulating Cellular Morphology Changes via Flow Matching
Yuhui Zhang, Yuchang Su, Chenyu Wang +8
Building a virtual cell capable of accurately simulating cellular behaviors in silico has long been a dream in computational biology. We introduce CellFlux, an image-generative mod…