3 papers
q-bio.PE2026
Combination therapy for colorectal cancer with anti-PD-L1 and cancer vaccine: A multiscale mathematical model of tumor-immune interactions
Chenghang Li, Haifeng Zhang, Xiulan Lai +1
The tumor-immune system plays a critical role in colorectal cancer progression. Recent preclinical and clinical studies showed that combination therapy with anti-PD-L1 and cancer v…
q-bio.QM2026
Quantitative cancer-immunity cycle modeling to optimize bevacizumab and atezolizumab combination therapy for advanced renal cell carcinoma
Lei Du, Chenghang Li, Jinzhi Lei
The incidence of advanced renal cell carcinoma(RCC) has been rising, presenting significant challenges due to the limited efficacy and severe side effects of traditional radiothera…
q-bio.QM2025
Mathematical modeling of tumor-immune interactions: methods, applications, and future perspectives
Chenghang Li, Jinzhi Lei
Mathematical oncology is a rapidly evolving interdisciplinary field that uses mathematical models to enhance our understanding of cancer dynamics, including tumor growth, metastasi…