Showing stat.MEShow all
2 papers · 1 filter
stat.ME2026
Some Bayesian Perspectives on Clinical Trials
Alexandra Sokolova, Vadim Sokolov, Nick Polson
We examine three landmark clinical trials -- ECMO, CALGB~49907, and I-SPY~2 -- through a unified Bayesian framework connecting prior specification, sequential adaptation, and decis…
stat.ME2026
E-values for Adaptive Clinical Trials: Anytime-Valid Monitoring in Practice
Alexandra Sokolova, Vadim Sokolov
Adaptive clinical trials rely on interim analyses, flexible stopping, and data-dependent design modifications that complicate statistical guarantees when fixed-horizon test statist…