13 papers
Democratizing and accelerating AI-driven pathology research through agentic intelligence
Jiabo Ma, Cheng Jin, Yihui Wang +19
Computational pathology has advanced rapidly with the emergence of foundation models, yet widespread adoption remains limited by substantial technical complexity and programming re…
Spatial Transcriptomics-Guided Alignment Enhances Molecular Profiling in Pathology Foundation Model
Fengtao Zhou, Yingxue Xu, Zhengyu Zhang +20
Comprehensive molecular profiling is essential for modern precision oncology but remains hindered by prohibitive costs, specimen exhaustion, and protracted turnaround times. While…
A Breast Vision Pathology Foundation Model for Real-world Clinical Utility
Yingxue Xu, Zhengyu Zhang, Xiuming Zhang +32
Pathology foundation models have shown strong retrospective performance, but whether such systems can support clinically relevant use remains unclear. This challenge is particularl…
A Deployment-Friendly Foundational Framework for Efficient Computational Pathology
Yu Cai, Cheng Jin, Jiabo Ma +25
Pathology foundation models (PFMs) generalize well across computational pathology tasks but remain costly for gigapixel whole-slide image analysis. Here, we present LitePath, a dep…
Investigating Data Pruning for Pretraining Biological Foundation Models at Scale
Yifan Wu, Jiyue Jiang, Xichen Ye +9
Biological foundation models (BioFMs), pretrained on large-scale biological sequences, have recently shown strong potential in providing meaningful representations for diverse down…
A Versatile Pathology Co-pilot via Reasoning Enhanced Multimodal Large Language Model
Zhe Xu, Ziyi Liu, Junlin Hou +13
Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with lang…