3 citations · 4 across the 6 of their papers we have counts for
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A Workflow for Evaluating Regional Treatment Effect Heterogeneity in Multi-Regional Clinical Trials
Cong Zhang, Meihua Long, Tianyu Zheng +8
Multi-regional clinical trials (MRCTs) enable efficient global drug development by assessing treatment effects across regions within a single protocol. While powered for overall ef…
Assessment of evidence against homogeneity in exhaustive subgroup treatment effect plots
Björn Bornkamp, Jiarui Lu, Frank Bretz
Exhaustive subgroup treatment effect plots are constructed by displaying all subgroup treatment effects of interest against subgroup sample size, providing a useful overview of the…
Data-driven controlled subgroup selection in clinical trials
Manuel M. Müller, Björn Bornkamp, Frank Bretz +7
Subgroup selection in clinical trials is essential for identifying patient groups that react differently to a treatment, thereby enabling personalised medicine. In particular, subg…