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20242026
most citedProtein Circuit Tracing via Cross-layer Transcoders

1 citations · 2 across the 3 of their papers we have counts for

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cs.LG2026

Circuit Tracing in Autoregressive Protein Language Models

Darin Tsui, William Deinzer, Daniel Saeedi +1

Protein language models (pLMs) can generate novel protein sequences with properties beyond those observed in nature, yet the mechanisms underlying protein generation remain poorly…

cs.LG20261 cited

Protein Circuit Tracing via Cross-layer Transcoders

Darin Tsui, Kunal Talreja, Daniel Saeedi +1

Protein language models (pLMs) have emerged as powerful predictors of protein structure and function. However, the computational circuits underlying their predictions remain poorly…

cs.LG2025

SpecMER: Fast Protein Generation with K-mer Guided Speculative Decoding

Thomas Walton, Darin Tsui, Aryan Musharaf +1

Autoregressive models have transformed protein engineering by enabling the generation of novel protein sequences beyond those found in nature. However, their sequential inference i…

cs.LG2025

Sparse Autoencoders for Low- Protein Function Prediction and Design

Darin Tsui, Kunal Talreja, Amirali Aghazadeh

Predicting protein function from amino acid sequence remains a central challenge in data-scarce (low-) regimes, limiting machine learning-guided protein design when only small a…

cs.LG2025

SHAP zero Explains Biological Sequence Models with Near-zero Marginal Cost for Future Queries

Darin Tsui, Aryan Musharaf, Yigit Efe Erginbas +2

The growing adoption of machine learning models for biological sequences has intensified the need for interpretable predictions, with Shapley values emerging as a theoretically gro…