27 citations · 77 across the 10 of their papers we have counts for
10 papers
Quantized Dehydration and the Determinants of Selectivity in the NaChBac Bacterial Sodium Channel
O. A. Fedorenko, I. Kh. Kaufman, W. A. T. Gibby +3
A discrete electrostatic/diffusion model has been developed to describe the selective permeation of ion channels, based on ionic Coulomb blockade (ICB) and quantised dehydration (Q…
Effect of Local Binding on Stochastic Transport in Ion Channels
I. Kh. Kaufman, W. A. T. Gibby, D. G. Luchinsky +1
Ionic Coulomb blockade (ICB) is an electrostatic phenomenon recently discovered in low-capacitance ion channels/nanopores. Depending on the fixed charge that is present, ICB strong…
Kinetic model of selectivity and conductivity of the KcsA filter
W. A. T. Gibby, D. G. Luchinsky, I. Kh. Kaufman A. Ward +1
We introduce a self-consistent multi-species kinetic theory based on the structure of the narrow voltage-gated potassium channel. Transition rates depend on a complete energy spect…
Ionic Coulomb blockade and anomalous mole fraction effect in NaChBac bacterial ion channels
I. Kh. Kaufman, O. A. Fedorenko, D. G. Luchinsky +3
We report an experimental study of the influences of the fixed charge and bulk ionic concentrations on the conduction of biological ion channels, and we consider the results within…
Statistical Theory of Selectivity and Conductivity in Biological Channels
D. G. Luchinsky, W. A. T. Gibby, I. Kaufman +2
We present an equilibrium statistical-mechanical theory of selectivity in biological ion channels. In doing so, we introduce a grand canonical ensemble for ions in a channel's sele…
Ionic Coulomb Blockade and Resonant Conduction in Biological Ion Channels
I. Kh. Kaufman, P. V. E. McClintock, R. S. Eisenberg
The conduction and selectivity of calcium/sodium ion channels are described in terms of ionic Coulomb blockade, a phenomenon based on charge discreteness and an electrostatic model…