7 papers · 1 filter
Oscillating concentrations suppress condensate coarsening
Mathias S. Heltberg, Lukas H. Kristensen, Mogens H. Jensen +1
Living cells utilize condensates to spatially concentrate molecules in response to dynamic signals. For instance, nuclear condensates respond to oscillations in transcription facto…
Intermediate physical interactions induce spatiotemporal dynamics in Turing patterns
Cathelijne ter Burg, David Zwicker
Turing patterns are a central paradigm for describing spatial patterns in nature. The corresponding theory of reaction-diffusion dynamics combines ideal diffusion with nonlinear re…
Roadmap for Condensates in Cell Biology
Dilimulati Aierken, Sebastian Aland, Stefano Bo +38
Biomolecular condensates govern essential cellular processes yet elude description by traditional equilibrium models. This roadmap, distilled from structured discussions at a works…
Physical interactions enable energy-efficient Turing patterns
Cathelijne ter Burg, David Zwicker
Patterns are ubiquitous in nature, but how they form is often unclear. Turing developed a seminal theory to explain patterns based on reactions that counteract the equalizing tende…
Physics of droplet regulation in biological cells
David Zwicker, Oliver W. Paulin, Cathelijne ter Burg
Droplet formation has emerged as an essential concept for the spatiotemporal organisation of biomolecules in cells. However, classical descriptions of droplet dynamics based on pas…
Active viscoelastic condensates provide controllable mechanical anchor points
Oliver W. Paulin, Júlia Garcia-Baucells, Luise Zieger +3
Many biological materials must couple mechanical strength with the ability to rapidly self-assemble at a specific location. In particular, biomolecular condensates readily self-ass…