Utilizing of protein splicing phenomenon for optimization of obtaining and purification of the recombinant human growth hormone

P. L. Starokadomskyy, O. V. Okunev, L. V. Dubey

Protein splicing is a post-translational autocatalystic excision of internal protein sequence (intein) with the subsequent ligation of the flanking polypeptides (exteins). The high…