2 papers
stat.ME2026
TWICEBEE: A Two-stage Intra-patient Curve-free Bayesian Decision-Theoretic Dose Escalation Design
Dehua Bi, Katherine Ryan, Sabine Heitzeneder +6
We propose a novel Phase I intra-patient dose-escalation design tailored for multi-cycle immunotherapy settings, in which toxicity at a fixed dose level is clinically expected to d…
cs.LG2026
SAGE-FM: A lightweight and interpretable spatial transcriptomics foundation model
Xianghao Zhan, Jingyu Xu, Yuanning Zheng +2
Spatial transcriptomics enables spatial gene expression profiling, motivating computational models that capture spatially conditioned regulatory relationships. We introduce SAGE-FM…