490 citations · 974 across the 26 of their papers we have counts for
4 papers · 1 filter
A Unified Statistical Framework for Single Cell and Bulk RNA Sequencing Data
Lingxue Zhu, Jing Lei, Bernie Devlin +1
Recent advances in technology have enabled the measurement of RNA levels for individual cells. Compared to traditional tissue-level bulk RNA-seq data, single cell sequencing yields…
Refining genetically inferred relationships using treelet covariance smoothing
Andrew Crossett, Ann B. Lee, Lambertus Klei +2
Recent technological advances coupled with large sample sets have uncovered many factors underlying the genetic basis of traits and the predisposition to complex disease, but much…
GemTools: A fast and efficient approach to estimating genetic ancestry
Lambertus Klei, Brian P. Kent, Nadine Melhem +2
To uncover the genetic basis of complex disease, individuals are often measured at a large number of genetic variants (usually SNPs) across the genome. GemTools provides computatio…
A Spectral Graph Approach to Discovering Genetic Ancestry
Ann B. Lee, Diana Luca, Kathryn Roeder
Mapping human genetic variation is fundamentally interesting in fields such as anthropology and forensic inference. At the same time patterns of genetic diversity confound efforts…