86 citations · 182 across the 7 of their papers we have counts for
7 papers
Critical phenomena in the temperature-pressure-crowding phase diagram of a protein
Andrei G. Gasic, Mayank M. Boob, Maxim B. Prigozhin +4
In the cell, proteins fold and perform complex functions through global structural rearrangements. Function requires a protein to be at the brink of stability to be susceptible to…
Crowding-induced Elongated Conformation of Urea-unfolded Apoazurin: Investigating the Role of Crowder Shape In Silico
Fabio C. Zegarra, Dirar Homouz, Andrei G. Gasic +4
Here, we show by solution nuclear magnetic resonance measurements that the urea-unfolded protein apoazurin becomes elongated when the synthetic crowding agent dextran 20 is present…
The impact of hydrodynamic interactions on protein folding rates depends on temperature
Fabio C. Zegarra, Dirar Homouz, Yossi Eliaz +2
We investigated the impact of hydrodynamic interactions (HI) on protein folding using a coarse-grained model. The extent of the impact of hydrodynamic interactions, whether it acce…
Multiscale Investigation of Chemical Interference in Proteins
Antonios Samiotakis, Dirar Homouz, Margaret S. Cheung
We developed a multiscale approach (MultiSCAAL) that integrates the potential of mean force (PMF) obtained from all-atomistic molecular dynamics simulations with a knowledge-based…
Macromolecular crowding modulates folding mechanism of alpha/beta protein apoflavodoxin
Dirar Homouz, Loren Stagg, Pernilla Wittung-Stafshede +1
Protein dynamics in cells may be different from that in dilute solutions in vitro since the environment in cells is highly concentrated with other macromolecules. This volume exclu…
Measurement of the 3-D Born-Oppenheimer Potential of a Proton in a Hydrogen Bonded System using Deep Inelastic Neutron Scattering: The Superprotonic Conductor Rb3H(SO4)2
D. Homouz, G. F. Reiter, J. Eckert +2
Born-Oppenheimer (BO) potential in any material. The proton potential surfaces in the hydrogen bonded superprotonic conductor Rb3H(SO4)2 are extracted from the momentum distributio…