160 citations · 264 across the 9 of their papers we have counts for
9 papers
Universal Relation Between Thermodynamic Driving Force and One-Way Fluxes in a Nonequilibrium Chemical Reaction with Complex Mechanism
Yongli Peng, Hong Qian, Daniel A. Beard +1
In nonequilibrium chemical reaction systems, a fundamental relationship between unbalanced kinetic one-way fluxes and thermodynamic chemical driving forces is believed to exists. H…
The Inferred Cardiogenic Gene Regulatory Network in the Mammalian Heart
Jason N. Bazil, Karl D. Stamm, Xing Li +3
Cardiac development is complex, multiscale process encompassing cell fate adoption, differentiation and morphogenesis. To elucidate pathways underlying this process, a recently dev…
Arterial stiffening provides sufficient explanation for primary hypertension
Klas H. Pettersen, Scott M. Bugenhagen, Javaid Nauman +2
Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity…
A Biophysical Model of the Mitochondrial ATP-Mg/Pi Carrier
Shivendra G. Tewari, Ranjan K. Dash, Daniel A. Beard +1
Mitochondrial adenine nucleotide (AdN) content is regulated through the Ca2+-activated, electroneutral ATP-Mg/Pi carrier (APC). The APC is a protein in the mitochondrial carrier su…
Specification, Construction, and Exact Reduction of State Transition System Models of Biochemical Processes
Scott M. Bugenhagen, Daniel A. Beard
Biochemical reaction systems may be viewed as discrete event processes characterized by a number of states and state transitions. These systems may be modeled as state transition s…
Analysis of Diffusion of Ras2 in Saccharomyces cerevisiae Using Fluorescence Recovery after Photobleaching
Kalyan C. Vinnakota, David A. Mitchell, Robert J. Deschenes +2
Binding, lateral diffusion and exchange are fundamental dynamic processes involved in protein association with cellular membranes. In this study, we developed numerical simulations…