3 papers
stat.ME2025
Estimate Time-Varying Exposure Effects via Ensemble Learning-based Marginal Structural Model with Application to Adolescent Cognitive Development Study
Zhiwei Zhao, Chixiang Chen, Shuo Chen
Evaluating the effects of time-varying exposures is essential for longitudinal studies. The effect estimation becomes increasingly challenging when dealing with hundreds of time-de…
stat.ME2025
A New Integrative Learning Framework for Integrating Multiple Secondary Outcomes into Primary Outcome Analysis: A Case Study on Liver Health
Daxuan Deng, Peisong Han, Shuo Chen +2
In the era of big data, secondary outcomes have become increasingly important alongside primary outcomes. These secondary outcomes, which can be derived from traditional endpoints…
stat.ME2024
Modeling Interconnected Modules in Multivariate Outcomes: Evaluating the Impact of Alcohol Intake on Plasma Metabolomics
Yifan Yang, Chixiang Chen, Hwiyoung Lee +2
Alcohol consumption has been shown to influence cardiovascular mechanisms in humans, leading to observable alterations in the plasma metabolomic profile. Regression models are comm…