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physics.med-ph2026

Robust Multicenter CT Radiogenomics for Dual EGFR and KRAS Prediction in Lung Cancer with Stability-Aware Modeling and SHAP Interpretation

Somayeh Sadat Mehrnia, Fatemeh Razavi, Helia Abedini +3

Accurate identification of EGFR and KRAS mutations is essential for precision therapy in non-small cell lung cancer (NSCLC), but tissue genotyping is invasive and may not capture t…

physics.med-ph2025

Semi-Supervised Radiomics for Glioblastoma IDH Mutation: Limited Labels, Data Sensitivity, and SHAP Interpretation

Amir Hossein Pouria, Shahram Taeb, Somayeh Sadat Mehrnia +4

Glioblastoma (GBM) is an aggressive brain tumor in which IDH mutation status is a key prognostic biomarker, but traditional testing requires invasive biopsies, emphasizing the need…

physics.med-ph2025

Handcrafted vs. Deep Radiomics vs. Fusion vs. Deep Learning: A Comprehensive Review of Machine Learning -Based Cancer Outcome Prediction in PET and SPECT Imaging

Mohammad R. Salmanpour, Somayeh Sadat Mehrnia, Sajad Jabarzadeh Ghandilu +7

Machine learning (ML), including deep learning (DL) and radiomics-based methods, is increasingly used for cancer outcome prediction with PET and SPECT imaging. However, the compara…

physics.med-ph2025

Robust Semi-Supervised CT Radiomics for Lung Cancer Prognosis: Cost-Effective Learning with Limited Labels and SHAP Interpretation

Mohammad R. Salmanpour, Amir Hossein Pouria, Sonia Falahati +7

Background: CT imaging is vital for lung cancer management, offering detailed visualization for AI-based prognosis. However, supervised learning SL models require large labeled dat…