6 papers
iSight: Towards expert-AI co-assessment for improved immunohistochemistry staining interpretation
Jacob S. Leiby, Jialu Yao, Pan Lu +17
Immunohistochemistry (IHC) provides information on protein expression in tissue sections and is commonly used to support pathology diagnosis and disease triage. While AI models for…
The Impact of Image Resolution on Biomedical Multimodal Large Language Models
Liangyu Chen, James Burgess, Jeffrey J Nirschl +2
Imaging technologies are fundamental to biomedical research and modern medicine, requiring analysis of high-resolution images across various modalities. While multimodal large lang…
A Large-Scale Vision-Language Dataset Derived from Open Scientific Literature to Advance Biomedical Generalist AI
Alejandro Lozano, Min Woo Sun, James Burgess +16
Despite the excitement behind biomedical artificial intelligence (AI), access to high-quality, diverse, and large-scale data - the foundation for modern AI systems - is still a bot…
MicroVQA: A Multimodal Reasoning Benchmark for Microscopy-Based Scientific Research
James Burgess, Jeffrey J Nirschl, Laura Bravo-Sánchez +20
Scientific research demands sophisticated reasoning over multimodal data, a challenge especially prevalent in biology. Despite recent advances in multimodal large language models (…
CellFlux: Simulating Cellular Morphology Changes via Flow Matching
Yuhui Zhang, Yuchang Su, Chenyu Wang +8
Building a virtual cell capable of accurately simulating cellular behaviors in silico has long been a dream in computational biology. We introduce CellFlux, an image-generative mod…
BIOMEDICA: An Open Biomedical Image-Caption Archive, Dataset, and Vision-Language Models Derived from Scientific Literature
Alejandro Lozano, Min Woo Sun, James Burgess +13
The development of vision-language models (VLMs) is driven by large-scale and diverse multimodal datasets. However, progress toward generalist biomedical VLMs is limited by the lac…