3 papers
q-bio.CB2025
Mechanical activity enables patterning and discrimination at the immune synapse
Tony Wong, Tom Chou, Suraj Shankar +1
Immune cells recognize and discriminate antigens through immunological synapses - dynamic intercellular junctions exhibiting highly organized receptor-ligand patterns. While much w…
q-bio.QM2025
Reconstructing Noisy Gene Regulation Dynamics Using Extrinsic-Noise-Driven Neural Stochastic Differential Equations
Jiancheng Zhang, Xiangting Li, Xiaolu Guo +6
Proper regulation of cell signaling and gene expression is crucial for maintaining cellular function, development, and adaptation to environmental changes. Reaction dynamics in cel…
q-bio.PE2024
Kinetic theories of state- and generation-dependent cell populations
Mingtao Xia, Tom Chou
We formulate a general, high-dimensional kinetic theory describing the internal state (such as gene expression or protein levels) of cells in a stochastically evolving population.…