3 papers
eess.IV2026
Multiscale reconstruction of protein conformations from cryo-EM images
David Y. W. Thong, Ozan Ãktem, Joakim Andén
We present a novel multiscale algorithm for directly recovering the atomic model structure of a protein from single-particle cryo-EM data. Our algorithm is able to estimate protein…
cs.CV2026
Protein Graph Neural Networks for Heterogeneous Cryo-EM Reconstruction
Jonathan Krook, Axel Janson, Joakim Andén +2
We present a geometry-aware method for heterogeneous single-particle cryogenic electron microscopy (cryo-EM) reconstruction that predicts atomic backbone conformations. To incorpor…
eess.SP2025
Moment-based Posterior Sampling for Multi-reference Alignment
Axel Janson, Joakim Andén
We propose a Bayesian approach to the problem of multi-reference alignment -- the recovery of signals from noisy, randomly shifted observations. While existing frequentist methods…