6 papers
Self-Driving Datasets: From 20 Million Papers to Nuanced Biomedical Knowledge at Scale
Haydn Jones, Yimeng Zeng, Alden Rose +11
Manually curated biomedical repositories -- spanning bioactivity, genomics, and chemistry -- are expensive to maintain, lag behind primary literature, and discard experimental cont…
Purely Agent-Driven Black-Box Optimization for Biological Design
Natalie Maus, Yimeng Zeng, Haydn Thomas Jones +11
Many key challenges in biological design -- such as small-molecule drug discovery, antimicrobial peptide development, and protein engineering -- can be framed as black-box optimiza…
Adversarial Query Synthesis via Bayesian Optimization
Jeffrey Tao, Yimeng Zeng, Haydn Thomas Jones +4
Benchmark workloads are extremely important to the database management research community, especially as more machine learning components are integrated into database systems. Here…
Covering Multiple Objectives with a Small Set of Solutions Using Bayesian Optimization
Natalie Maus, Kyurae Kim, Yimeng Zeng +5
In multi-objective black-box optimization, the goal is typically to find solutions that optimize a set of black-box objective functions, , simultaneously. Trad…
Large Scale Multi-Task Bayesian Optimization with Large Language Models
Yimeng Zeng, Natalie Maus, Haydn Thomas Jones +7
In multi-task Bayesian optimization, the goal is to leverage experience from optimizing existing tasks to improve the efficiency of optimizing new ones. While approaches using mult…
Learned Offline Query Planning via Bayesian Optimization
Jeffrey Tao, Natalie Maus, Haydn Jones +3
Analytics database workloads often contain queries that are executed repeatedly. Existing optimization techniques generally prioritize keeping optimization cost low, normally well…