234 citations · 632 across the 7 of their papers we have counts for
8 papers · 1 filter
Physical Properties of Biological Membranes
Thomas Heimburg
Biological membranes mainly consist of lipids and proteins. While the proteins have many functions as single molecules, the membrane as a whole displays physical properties that ca…
The temperature dependence of lipid membrane permeability, its quantized nature, and the influence of anesthetics
Andreas Blicher, Katarzyna Wodzinska, Matthias Fidorra +2
We investigate the permeability of lipid membranes for fluorescence dyes and ions. We find that permeability reaches a maximum close to the chain melting transition of the membrane…
Melting of Single Lipid Components in Binary Lipid Mixtures: A Comparison between FTIR Spectroscopy, DSC and Monte Carlo Simulations
M. Fidorra, T. Heimburg, H. M. Seeger
Monte Carlo (MC) Simulations, Differential Scanning Calorimetry (DSC) and Fourier Transform InfraRed (FTIR) spectroscopy were used to study the melting behavior of single lipid com…
The influence of anesthetics, neurotransmitters and antibiotics on the relaxation processes in lipid membranes
Heiko M. Seeger, Marie L. Gudmundsson, Thomas Heimburg
In the proximity of melting transitions of artificial and biological membranes fluctuations in enthalpy, area, volume and concentration are enhanced. This results in domain formati…
The thermodynamics of general anesthesia
Thomas Heimburg, Andrew D. Jackson
It is known that the action of general anesthetics is proportional to their partition coefficient in lipid membranes (Meyer-Overton rule). This solubility is, however, directly rel…
On the action potential as a propagating density pulse and the role of anesthetics
Thomas Heimburg, Andrew D. Jackson
The Hodgkin-Huxley model of nerve pulse propagation relies on ion currents through specific resistors called ion channels. We discuss a number of classical thermodynamic findings o…