2 papers
stat.ME2026
Index Date Imputation for Survival Analysis in Externally Controlled Trials with Delayed Treatment Initiation
Q. Le Coent, G. L. Rosner, M-C. Wang +1
Externally controlled trials compare outcomes from a single-arm trial with external controls drawn from historical trials, registries, or observational studies. For time-to-event e…
stat.ME2025
Tutorial for Surrogate Endpoint Validation Using Joint modeling and Mediation Analysis
Quentin Le Coent, Virginie Rondeau, Catherine Legrand
The use of valid surrogate endpoints is an important stake in clinical research to help reduce both the duration and cost of a clinical trial and speed up the evaluation of interes…