4 papers
Immunological recognition by artificial neural networks
Jin Xu, Junghyo Jo
The binding affinity between the T-cell receptors (TCRs) and antigenic peptides mainly determines immunological recognition. It is not a trivial task that T cells identify the digi…
Broad cross-reactivity of the T-cell repertoire achieves specific and sufficiently rapid target searching
Jin Xu, Junghyo Jo
The molecular recognition of T-cell receptors is the hallmark of the adaptive immunity. Given the finiteness of the T-cell repertoire, individual T-cell receptors are necessary to…
A Local Counter-Regulatory Motif Modulates the Global Phase of Hormonal Oscillations
Dong-Ho Park, Taegeun Song, Danh-Tai Hoang +2
Counter-regulatory elements maintain dynamic equilibrium ubiquitously in living systems. The most prominent example, which is critical to mammalian survival, is that of pancreatic…
Local complexity predicts global synchronization of hierarchically networked oscillators
Jin Xu, Dong-Ho Park, Junghyo Jo
We study the global synchronization of hierarchically-organized Stuart-Landau oscillators, where each subsystem consists of three oscillators with activity-dependent couplings. We…