431 citations · 1.9k across the 27 of their papers we have counts for
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Robustness of synthetic oscillators in growing and dividing cells
Joris Paijmans, David K Lubensky, Pieter Rein ten Wolde
Synthetic biology sets out to implement new functions in cells, and to develop a deeper understanding of biological design principles. In 2000, Elowitz and Leibler showed that by r…
A Thermodynamically consistent model of the post-translational Kai circadian clock
Joris Paijmans, David K Lubensky, Pieter Rein ten Wolde
The principal pacemaker of the circadian clock of the cyanobacterium S. elongatus is a protein phosphorylation cycle consisting of three proteins, KaiA, KaiB and KaiC. KaiC forms a…
Period Robustness and Entrainability of the Kai System to Changing Nucleotide Concentrations
Joris Paijmans, David K Lubensky, Pieter Rein ten Wolde
Circadian clocks must be able to entrain to time-varying signals to keep their oscillations in phase with the day-night rhythm. On the other hand, they must also exhibit input comp…
Vertex stability and topological transitions in vertex models of foams and epithelia
Meryl A. Spencer, Zahera Jabeen, David K. Lubensky
In computer simulations of dry foams and of epithelial tissues, vertex models are often used to describe the shape and motion of individual cells. Although these models have been w…