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cs.AI2026
Treatment Response Optimized Clinical Decision Support AI System via Digital Twin Simulation
Xinyu Qin, Anil K. Sood, Ruiheng Yu +3
Clinical decision support AI systems (CDSASs) must adapt to evolving patient conditions in real-time while adhering to strict safety constraints. We present an online adaptive fram…
cs.AI2025
Reinforcement Learning enhanced Online Adaptive Clinical Decision Support via Digital Twin powered Policy and Treatment Effect optimized Reward
Xinyu Qin, Ruiheng Yu, Lu Wang
Clinical decision support must adapt online under safety constraints. We present an online adaptive tool where reinforcement learning provides the policy, a patient digital twin pr…
cs.AI2025
Explainable Counterfactual Reasoning in Depression Medication Selection at Multi-Levels (Personalized and Population)
Xinyu Qin, Mark H. Chignell, Alexandria Greifenberger +5
Background: This study investigates how variations in Major Depressive Disorder (MDD) symptoms, quantified by the Hamilton Rating Scale for Depression (HAM-D), causally influence t…