4 papers · 1 filter
AI in Proton Therapy Treatment Planning: A Review
Yuzhen Ding, Hongying Feng, Martin Bues +12
Purpose: Proton therapy provides superior dose conformity compared to photon therapy, but its treatment planning is challenged by sensitivity to anatomical changes, setup/range unc…
Causal Machine Learning Analysis of Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis in Head and Neck Cancer Radiotherapy
Jingyuan Chen, Zhong Liu, Yunze Yang +8
Mandible Osteoradionecrosis (ORN) is one of the most severe adverse events (AEs) for head and neck (H&N) cancer radiotherapy. Previous retrospective investigations on real-world da…
Diffusion Transformer-based Universal Dose Denoising for Pencil Beam Scanning Proton Therapy
Yuzhen Ding, Jason Holmes, Hongying Feng +13
Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anat…
Robust Optimization for Spot Scanning Proton Therapy based on Dose-Linear Energy Transfer (LET) Volume Constraints
Jingyuan Chen, Yunze Yang, Hongying Feng +8
Purpose: Historically, spot scanning proton therapy (SSPT) treatment planning utilizes dose volume constraints and linear-energy-transfer (LET) volume constraints separately to bal…