1.3k citations · 3.9k across the 27 of their papers we have counts for
4 papers · 1 filter
Python Unleashed on Systems Biology
Christopher R. Myers, Ryan N. Gutenkunst, James. P. Sethna
We have built an open-source software system for the modeling of biomolecular reaction networks, SloppyCell, which is written in Python and makes substantial use of third-party lib…
Python for Education: Computational Methods for Nonlinear Systems
Christopher R. Myers, James. P. Sethna
We describe a novel, interdisciplinary, computational methods course that uses Python and associated numerical and visualization libraries to enable students to implement simulatio…
Extracting falsifiable predictions from sloppy models
Ryan N. Gutenkunst, Fergal P. Casey, Joshua J. Waterfall +2
Successful predictions are among the most compelling validations of any model. Extracting falsifiable predictions from nonlinear multiparameter models is complicated by the fact th…
Universally Sloppy Parameter Sensitivities in Systems Biology
Ryan N. Gutenkunst, Joshua J. Waterfall, Fergal P. Casey +3
Quantitative computational models play an increasingly important role in modern biology. Such models typically involve many free parameters, and assigning their values is often a s…