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q-bio.MN2021
Network analytics for drug repurposing in COVID-19
Nicoleta Siminea, Victor Popescu, Jose Angel Sanchez Martin +14
To better understand the potential of drug repurposing in COVID-19, we analyzed control strategies over essential host factors for SARS-CoV-2 infection. We constructed comprehensiv…
q-bio.MN2007
Modeling the effects of HIV-1 virions and proteins on Fas-induced apoptosis of infected cells
John Jack, Andrei Paun
We report a first in modeling and simulation of the effects of the HIV proteins on the (caspase dependent) apoptotic pathway in infected cells. This work is novel and is an extensi…