2 papers
q-bio.BM2018
A natural upper bound to the accuracy of predicting protein stability changes upon mutations
Ludovica Montanucci, Pier Luigi Martelli, Nir Ben-Tal +1
Accurate prediction of protein stability changes upon single-site variations (DDG) is important for protein design, as well as our understanding of the mechanism of genetic disease…
q-bio.BM2007
In silico evidence of the relationship between miRNAs and siRNAs
Ludovica Montanucci, Piero Fariselli, Pier Luigi Martelli +2
Both short interfering RNAs (siRNAs) and microRNAs (miRNAs) mediate the repression of specific sequences of mRNA through the RNA interference pathway. In the last years several exp…