9 papers
BioHarness: Substrate-Aware Evidence Assembly for Biomedical Question Answering across Literature, Knowledge Bases, and Biological Atlases
Meng Xiao, Chuan Qin, Jinmiao Chen +3
Motivation: Biomedical question answering often requires evidence beyond topically retrieved literature, including gene alias resolution, database identifier normalization, and atl…
SciHorizon-GENE: Benchmarking LLM for Life Sciences Inference from Gene Knowledge to Functional Understanding
Xiaohan Huang, Meng Xiao, Chuan Qin +4
Large language models (LLMs) have shown growing promise in biomedical research, particularly for knowledge-driven interpretation tasks. However, their ability to reliably reason fr…
From Snapshots to Trajectories: Learning Single-Cell Gene Expression Dynamics via Conditional Flow Matching
Siyu Pu, Qingqing Long, Xiaohan Huang +7
Single-cell RNA sequencing (scRNA-seq) provides high-dimensional profiles of cellular states, enabling data-driven modeling of cellular dynamics over time. In practice, time-resolv…
DeepEra: A Deep Evidence Reranking Agent for Scientific Retrieval-Augmented Generated Question Answering
Haotian Chen, Qingqing Long, Siyu Pu +6
With the rapid growth of scientific literature, scientific question answering (SciQA) has become increasingly critical for exploring and utilizing scientific knowledge. Retrieval-A…
Knowledge-Driven Agentic Scientific Corpus Distillation Framework for Biomedical Large Language Models Training
Meng Xiao, Xunxin Cai, Qingqing Long +3
Corpus distillation for biomedical large language models (LLMs) seeks to address the pressing challenge of insufficient quantity and quality in open-source annotated scientific cor…
Knowledge Hierarchy Guided Biological-Medical Dataset Distillation for Domain LLM Training
Xunxin Cai, Chengrui Wang, Qingqing Long +2
The rapid advancement of large language models (LLMs) in biological-medical applications has highlighted a gap between their potential and the limited scale and often low quality o…