177 citations · 651 across the 25 of their papers we have counts for
25 papers
Enhancer-promoter proximity predicts transcriptional competence but not transcriptional output in the Drosophila brain
Olivier Messina, Loucif Remini, Christopher H. Bohrer +4
How 3D genome architecture contributes to transcriptional specificity across neuronal cell types remains unclear. Here, we used multiplexed chromatin tracing to map chromatin archi…
Chain decay and rates disorder in the totally asymmetric simple exclusion process
Yahaya Ibrahim, Jérôme Dorignac, Fred Geniet +5
We theoretically study the Totally Asymmetric Exclusion Process (TASEP) with quenched jumping rates disorder and finite lifetime chain. TASEP is widely used to model the translatio…
Signature of (anti)cooperativity in the stochastic fluctuations of small systems: application to the bacterial flagellar motor
María-José Franco-Oñate, Andrea Parmeggiani, Jérôme Dorignac +6
The cooperative binding of molecular agents onto a substrate is pervasive in living systems. To study whether a system shows cooperativity, one can rely on a fluctuation analysis o…
ATP-driven separation of liquid phase condensates in bacteria
B. Guilhas, J. C. Walter, J. Rech +8
Liquid-liquid phase separated (LLPS) states are key to compartmentalise components in the absence of membranes, however it is unclear whether LLPS condensates are actively and spec…
Modelling the effect of ribosome mobility on the rate of protein synthesis
Olivier Dauloudet, Izaak Neri, Jean-Charles Walter +3
Translation is one of the main steps in the synthesis of proteins. It consists of ribosomes that translate sequences of nucleotides encoded on mRNA into polypeptide sequences of am…
Modeling supercoiled DNA interacting with an anchored cluster of proteins: towards a quantitative estimation of chromosomal DNA supercoiling
Jean-Charles Walter, Thibaut Lepage, Jérôme Dorignac +5
We investigate the measurement of DNA supercoiling density () along chromosomes using interaction frequencies between DNA and DNA-anchored clusters of proteins. Specifically, we…