3 papers
q-bio.QM2025
Optimal experiment design for practical parameter identifiability and model discrimination
Yue Liu, Philip K. Maini, Ruth E. Baker
Mechanistic mathematical models of biological systems usually contain a number of unknown parameters whose values need to be estimated from available experimental data in order for…
math.ST2025
Optimal experimental design for parameter estimation in the presence of observation noise
Jie Qi, Ruth E. Baker
Using mathematical models to assist in the interpretation of experiments is becoming increasingly important in research across applied mathematics, and in particular in biology and…
q-bio.PE2025
Modelling the impact of phenotypic heterogeneity on cell migration: a continuum framework derived from individual-based principles
Rebecca M. Crossley, Philip K. Maini, Ruth E. Baker
Collective cell migration plays a crucial role in numerous biological processes, including tumour growth, wound healing, and the immune response. Often, the migrating population co…