6 papers
Dual-View Inference Attack: Machine Unlearning Amplifies Privacy Exposure
Lulu Xue, Shengshan Hu, Linqiang Qian +6
Machine unlearning is a newly popularized technique for removing specific training data from a trained model, enabling it to comply with data deletion requests. While it protects t…
HiF-DTA: Hierarchical Feature Learning Network for Drug-Target Affinity Prediction
Minghui Li, Yuanhang Wang, Peijin Guo +3
Accurate prediction of Drug-Target Affinity (DTA) is crucial for reducing experimental costs and accelerating early screening in computational drug discovery. While sequence-based…
ADVEDM:Fine-grained Adversarial Attack against VLM-based Embodied Agents
Yichen Wang, Hangtao Zhang, Hewen Pan +7
Vision-Language Models (VLMs), with their strong reasoning and planning capabilities, are widely used in embodied decision-making (EDM) tasks in embodied agents, such as autonomous…
Uncertainty-Aware Metabolic Stability Prediction with Dual-View Contrastive Learning
Peijin Guo, Minghui Li, Hewen Pan +6
Accurate prediction of molecular metabolic stability (MS) is critical for drug research and development but remains challenging due to the complex interplay of molecular interactio…
Multi-Modality Representation Learning for Antibody-Antigen Interactions Prediction
Peijin Guo, Minghui Li, Hewen Pan +6
While deep learning models play a crucial role in predicting antibody-antigen interactions (AAI), the scarcity of publicly available sequence-structure pairings constrains their ge…
ViDTA: Enhanced Drug-Target Affinity Prediction via Virtual Graph Nodes and Attention-based Feature Fusion
Minghui Li, Zikang Guo, Yang Wu +5
Drug-target interaction is fundamental in understanding how drugs affect biological systems, and accurately predicting drug-target affinity (DTA) is vital for drug discovery. Recen…