9 papers
Mesoscopic Light Localization and Inverse Participation Ratio Analysis of Tissue Structural Disorder for Optical Cancer Detection
Santanu Maity, Mousa Alrubayan, Prabhakar Pradhan
We introduce a mesoscopic physics-based framework that transforms conventional transmission optical micrographs into quantitative maps of tissue structural heterogeneity using the…
Quantitative Characterization of Brain Tissue Alterations in Brain Cancer Using Fractal, Multifractal, and IPR Metrics
Mousa Alrubayan, Santanu Maity, Prabhakar Pradhan
We studied the structural alterations between healthy and diseased brain tissues using a multiparametric framework combining fractal analysis, fractal functional transformation, mu…
Alterations of brain tissue structural complexity and disorder in Alzheimer's disease (AD): Fractal, multifractal, fractal transformation, and disorder strength analyses
Santanu Maity, Mousa Alrubayan, Mohammad Moshahid Khan +1
Alzheimer's disease (AD) is characterized by progressive microstructural deterioration in brain tissue, yet conventional imaging and histopathology often lack the sensitivity neede…
Alterations of brain tissue structural complexity and disorder in Parkinson disease (PD): Fractal, multifractal, fractal transformation, and disorder strength analyses
Santanu Maity, Mousa Alrubayan, Mohammad Moshahid Khan +1
Parkinson disease (PD) is marked by progressive neurodegeneration, yet early and subtle structural alterations in brain tissue remain difficult to detect with conventional imaging…
Decoding Breast Cancer in X-ray Mammograms: A Multi-Parameter Approach Using Fractals, Multifractals, and Structural Disorder Analysis
Santanu Maity, Mousa Alrubayan, Prabhakar Pradhan
We explored the fractal and multifractal characteristics of breast mammogram micrographs to identify quantitative biomarkers associated with breast cancer progression. In addition…
Evaluation and optimization of deep learning models for enhanced detection of brain cancer using transmission optical microscopy of thin brain tissue samples
Mohnish Sao, Mousa Alrubayan, Prabhakar Pradhan
Optical transmission spectroscopy is one method to understand brain tissue structural properties from brain tissue biopsy samples, yet manual interpretation is resource intensive a…
Automated grading and staging of ovarian cancer using deep learning on the transmission optical microscopy bright-field images of thin biopsy tissue samples
Ashmit K Mishra, Mousa Alrubayan, Prabhakar Pradhan
Ovarian cancer remains a challenging malignancy to diagnose and manage, with prognosis heavily dependent on the stage at detection. Accurate grading and staging, primarily based on…
Optical probing of fractal and multifractal connection to structural disorder in weakly optical disordered media: Application to cancer detection
Santanu Maity, Mousa Alrubayan, Ishmael Apachigwao +2
The light scattering experiment establishes a relationship between refractive index fluctuations and fractal dimension in weakly scattering tissue-like media. Based on the box-coun…
An AI-directed analytical study on the optical transmission microscopic images of Pseudomonas aeruginosa in planktonic and biofilm states
Bidisha Sengupta, Mousa Alrubayan, Yibin Wang +5
Biofilms are resistant microbial cell aggregates that pose risks to health and food industries and produce environmental contamination. Accurate and efficient detection and prevent…