7 papers
Causal discovery identifies pathways linking physical activity to dementia risk in the UK BioBank
Wasif Khan, Panayiotis V. Benos, Joshua K. Wong +1
Physical Activity (PA) is consistently associated with lower risk of dementia, yet the mechanism linking PA to dementia prevention remain incomopletely understood. Here, we integra…
Prediction of Alzheimer's Disease Risk Factors from Retinal Images via Deep Learning: Development and Validation of Biologically Relevant Morphological Associations in the UK Biobank
Seowung Leem, Yunchao Yang, Adam J. Woods +1
The systemic, metabolic, lifestyle factors have established associations with Alzheimer's Disease (AD) through epidemiologic and AD-specific biomarker studies. Whether colored fund…
A General Bézier Tree Encoding Counterfactual Framework for Retinal-Vessel-Mediated Disease Analysis
Tan Su, Ethan Elio Meidinger, Lin Gu +1
The geometry of the retinal vessel is a key biomarker of vascular diseases, yet clinical evidence remains primarily observational. Existing generative counterfactuals intervene onl…
Association of Timing and Duration of Moderate-to-Vigorous Physical Activity with Cognitive Function and Brain Aging: A Population-Based Study Using the UK Biobank
Wasif Khan, Lin Gu, Noah Hammarlund +3
Physical activity is a modifiable lifestyle factor with potential to support cognitive resilience. However, the association of moderate-to-vigorous physical activity (MVPA) intensi…
Revealing Neurocognitive and Behavioral Patterns by Unsupervised Manifold Learning from Dynamic Brain Data
Zixia Zhou, Junyan Liu, Wei Emma Wu +9
Dynamic brain data, teeming with biological and functional insights, are becoming increasingly accessible through advanced measurements, providing a gateway to understanding the in…
Physiology-Informed Generative Multi-Task Network for Contrast-Free CT Perfusion
Wasif Khan, John Rees, Kyle B. See +12
Perfusion imaging is extensively utilized to assess hemodynamic status and tissue perfusion in various organs. Computed tomography perfusion (CTP) imaging plays a key role in the e…
Paleoinspired Vision: From Exploring Colour Vision Evolution to Inspiring Camera Design
Junjie Zhang, Zhimin Zong, Lin Gu +8
The evolution of colour vision is captivating, as it reveals the adaptive strategies of extinct species while simultaneously inspiring innovations in modern imaging technology. In…