activity
20242026
most citedDual Photonics Probing of Nano- to Submicron-Scale Structural Alterations in Human Brain Tissues or Cells and Chromatin or DNA with the Progression of Alzheimers Disease

2 citations · 2 across the 12 of their papers we have counts for

collaborators

13 papers

physics.med-ph2026

Mesoscopic Light Localization and Inverse Participation Ratio Analysis of Tissue Structural Disorder for Optical Cancer Detection

Santanu Maity, Mousa Alrubayan, Prabhakar Pradhan

We introduce a mesoscopic physics-based framework that transforms conventional transmission optical micrographs into quantitative maps of tissue structural heterogeneity using the…

physics.med-ph2025

Quantitative Characterization of Brain Tissue Alterations in Brain Cancer Using Fractal, Multifractal, and IPR Metrics

Mousa Alrubayan, Santanu Maity, Prabhakar Pradhan

We studied the structural alterations between healthy and diseased brain tissues using a multiparametric framework combining fractal analysis, fractal functional transformation, mu…

physics.med-ph2025

Alterations of brain tissue structural complexity and disorder in Alzheimer's disease (AD): Fractal, multifractal, fractal transformation, and disorder strength analyses

Santanu Maity, Mousa Alrubayan, Mohammad Moshahid Khan +1

Alzheimer's disease (AD) is characterized by progressive microstructural deterioration in brain tissue, yet conventional imaging and histopathology often lack the sensitivity neede…

physics.med-ph2025

Alterations of brain tissue structural complexity and disorder in Parkinson disease (PD): Fractal, multifractal, fractal transformation, and disorder strength analyses

Santanu Maity, Mousa Alrubayan, Mohammad Moshahid Khan +1

Parkinson disease (PD) is marked by progressive neurodegeneration, yet early and subtle structural alterations in brain tissue remain difficult to detect with conventional imaging…

physics.med-ph2025

Comprehensive Multimodal and Multiscale Analysis of Alzheimer Disease in 5xFAD Mice: Optical Spectroscopies, TEM, Neuropathological, and Behavioral Investigations

Dhruvil Solanki, Ishmael Apachigawo, Sazzad Khan +8

Alzheimer disease (AD) is considered one of the leading causes of death in the United States, and there is no effective cure for it. Understanding the neuropathological mechanisms…

physics.med-ph2025

Decoding Breast Cancer in X-ray Mammograms: A Multi-Parameter Approach Using Fractals, Multifractals, and Structural Disorder Analysis

Santanu Maity, Mousa Alrubayan, Prabhakar Pradhan

We explored the fractal and multifractal characteristics of breast mammogram micrographs to identify quantitative biomarkers associated with breast cancer progression. In addition…

physics.med-ph2025

Evaluation and optimization of deep learning models for enhanced detection of brain cancer using transmission optical microscopy of thin brain tissue samples

Mohnish Sao, Mousa Alrubayan, Prabhakar Pradhan

Optical transmission spectroscopy is one method to understand brain tissue structural properties from brain tissue biopsy samples, yet manual interpretation is resource intensive a…

physics.med-ph2025

Automated grading and staging of ovarian cancer using deep learning on the transmission optical microscopy bright-field images of thin biopsy tissue samples

Ashmit K Mishra, Mousa Alrubayan, Prabhakar Pradhan

Ovarian cancer remains a challenging malignancy to diagnose and manage, with prognosis heavily dependent on the stage at detection. Accurate grading and staging, primarily based on…

physics.med-ph2024

Photonics detection of molecular-specific spatial structural alterations in cell nuclei due to chronic alcoholism and probiotics treatments on colon cancer via a light localization method using confocal imaging

Ishmael Apachigawo, Dhruvil Solanki, Santanu Maity +3

Photonics/light localization techniques are important in understanding the structural changes in biological tissues at the nano- to sub-micron scale. It is now known that structura…

physics.optics2024

Optical probing of fractal and multifractal connection to structural disorder in weakly optical disordered media: Application to cancer detection

Santanu Maity, Mousa Alrubayan, Ishmael Apachigwao +2

The light scattering experiment establishes a relationship between refractive index fluctuations and fractal dimension in weakly scattering tissue-like media. Based on the box-coun…

physics.med-ph2024

Optical detection of the spatial structural alteration in the human brain tissues and cells and DNA and chromatin due to Parkinsons disease

Fatemah Alharthi, Dhruvil Solanki, Ishmael Apachigawo +3

Parkinsons disease (PD) is considered one of the most frequent neurological diseases in the world. There is a need to study the early and efficient biomarkers of Parkinsons, such a…

physics.med-ph2024

An AI-directed analytical study on the optical transmission microscopic images of Pseudomonas aeruginosa in planktonic and biofilm states

Bidisha Sengupta, Mousa Alrubayan, Yibin Wang +5

Biofilms are resistant microbial cell aggregates that pose risks to health and food industries and produce environmental contamination. Accurate and efficient detection and prevent…

physics.med-ph2024★ 2 cited

Dual Photonics Probing of Nano- to Submicron-Scale Structural Alterations in Human Brain Tissues or Cells and Chromatin or DNA with the Progression of Alzheimers Disease

Fatemah Alharthi, Ishmael Apachigawo, Dhruvil Solanki +4

Understanding alterations in structural disorders in tissue or cells or building blocks, such as DNA or chromatin in the human brain, at the nano to submicron level provides us wit…