activity
20242026
most citedStructure-Enhanced Protein Instruction Tuning: Towards General-Purpose Protein Understanding with LLMs

2 citations · 6 across the 7 of their papers we have counts for

collaborators

9 papers

cs.CV2026

SegBanana: Steering Unified Multimodal Models into Medical Segmenters

Xiaoye Liang, Ye Yan, Mingze Yin +5

Medical image segmentation remains challenging in practical deployment, as models often struggle to generalize beyond the distributions covered by their training data and high-qual…

cs.LG2025

A Generalist Cross-Domain Molecular Learning Framework for Structure-Based Drug Discovery

Yiheng Zhu, Mingyang Li, Junlong Liu +7

Structure-based drug discovery (SBDD) is a systematic scientific process that develops new drugs by leveraging the detailed physical structure of the target protein. Recent advance…

cs.LG2024★ 1 cited

ProtCLIP: Function-Informed Protein Multi-Modal Learning

Hanjing Zhou, Mingze Yin, Wei Wu +5

Multi-modality pre-training paradigm that aligns protein sequences and biological descriptions has learned general protein representations and achieved promising performance in var…

cs.LG2024

SALM: Sequence-Structure Pre-trained Large Language Model for Comprehensive Antibody Representation Learning

Mingze Yin, Hanjing Zhou, Jialu Wu +8

Antibodies safeguard our health through their precise and potent binding to specific antigens, demonstrating promising therapeutic efficacy in the treatment of numerous diseases, i…

cs.LG2024★ 1 cited

Bridge-IF: Learning Inverse Protein Folding with Markov Bridges

Yiheng Zhu, Jialu Wu, Qiuyi Li +7

Inverse protein folding is a fundamental task in computational protein design, which aims to design protein sequences that fold into the desired backbone structures. While the deve…

cs.CL2024★ 2 cited

Structure-Enhanced Protein Instruction Tuning: Towards General-Purpose Protein Understanding with LLMs

Wei Wu, Chao Wang, Liyi Chen +6

Proteins, as essential biomolecules, play a central role in biological processes, including metabolic reactions and DNA replication. Accurate prediction of their properties and fun…

cs.AI2024

Multi-Modal CLIP-Informed Protein Editing

Mingze Yin, Hanjing Zhou, Yiheng Zhu +8

Proteins govern most biological functions essential for life, but achieving controllable protein discovery and optimization remains challenging. Recently, machine learning-assisted…

cs.CV2024★ 2 cited

Group-On: Boosting One-Shot Segmentation with Supportive Query

Hanjing Zhou, Mingze Yin, Danny Chen +2

One-shot semantic segmentation aims to segment query images given only ONE annotated support image of the same class. This task is challenging because target objects in the support…

q-bio.BM2024

Generative AI for Controllable Protein Sequence Design: A Survey

Yiheng Zhu, Zitai Kong, Jialu Wu +6

The design of novel protein sequences with targeted functionalities underpins a central theme in protein engineering, impacting diverse fields such as drug discovery and enzymatic…