11 papers
Boundary Embedding Shaping with Adaptive Contrastive Learning for Graph Structural Disentanglement
Jiaqing Chen, Zidu Yin, Yichao Cai +4
Graph neural networks (GNNs) excel at aggregating neighbor information for classification, yet their performance is hindered by graph structural entanglement, where spurious correl…
The Geometric Mechanics of Contrastive Representation Learning: Alignment Potentials, Entropic Dispersion, and Cross-modal Divergence
Yichao Cai, Zhen Zhang, Yuhang Liu +1
While InfoNCE underlies modern contrastive learning, its geometric mechanisms remain under-characterized beyond the canonical alignment--uniformity decomposition. We develop a meas…
Learning Latent Dynamical Causal Processes for Single-Cell Perturbation Prediction
Wenkang Jiang, Yuhang Liu, Erdun Gao +3
Single-cell perturbation prediction aims to infer how cells respond to unseen interventions and to achieve out-of-distribution (OOD) generalization, providing a computational route…
S2Aligner: Pair-Efficient and Transferable Pre-Training for Sparse Text-Attributed Graphs
Yuhan Wang, Haopeng Zhang, Yibo Ding +6
Pre-training on text-attributed graphs (TAGs) is central to building transferable graph foundation models, where LLM-as-Aligner methods align graph and text representations through…
What Makes a Representation Good for Single-Cell Perturbation Prediction?
Wenkang Jiang, Yuhang Liu, Yichao Cai +5
Single-cell perturbation modeling is fundamental for understanding and predicting cellular responses to genetic perturbations. However, existing approaches, from causal representat…
I Predict Therefore I Am: Is Next Token Prediction Enough to Learn Human-Interpretable Concepts from Data?
Yuhang Liu, Dong Gong, Yichao Cai +6
Recent empirical evidence shows that LLM representations encode human-interpretable concepts. Nevertheless, the mechanisms by which these representations emerge remain largely unex…