3 papers
q-bio.QM2025
Inferring and predicting Fried physical frailty phenotype deficits
Glen Pridham, Kenneth Rockwood, Andrew Rutenberg
We predict the Fried physical frailty phenotype health deficits (FPFP5: slow gait, weakness, weight loss, low activity, and exhaustion) using two measures of frailty: frailty index…
q-bio.QM2024
Aging health dynamics cross a tipping point near age 75
Glen Pridham, Kenneth Rockwood, Andrew Rutenberg
Aging includes both continuous gradual decline, such as in physiological function, together with major deficit onset events such as morbidity, disability and ultimately death. Thes…
q-bio.QM2024
Systems-level health of patients living with end-stage kidney disease using standard lab values
Glen Pridham, Karthik K. Tennankore, Kenneth Rockwood +2
We present a systems-level analysis of end-stage kidney disease (ESKD) with a dynamical network analysis of 14 commonly measured blood-based biomarkers in patients undergoing regul…